Publications

Highlights

(For a selected list see below or for the full list go to Google Scholar)

Ray optics for gliders

Tyler shows how gliders that encounter friction gradients behave much in the same way as ray optics. This allows one to predict gliding trajectories and organize gliders, by designing gradients that act as lenses and prisms.

T.D. Ross, D. Osmanović, J.F. Brady, P.W.K. Rothemund

ACS Nano XX, XXX (2022)

Absolute and arbitrary orientation of single molecule shapes

We show that we can position DNA origami on silica surfaces with absolute (all degrees of freedom are specified) and arbitrary (every molecule’s orientation is independently specified).

A. Gopinath, C. Thachuk, A. Mitskovets, H.A. Atwater, D. Kirkpatrick, P.W.K. Rothemund

Science 371, 6531 (2021)

Engineering and mapping nanocavity emission via precision placement of DNA origami

Being able to precisely position DNA origami onto lithographically patterned surfaces, allowed us to program the intensity of tens of thousands of photonic crystal cavities.

A. Gopinath, E. Miyazono, A. Faraon, P.W.K. Rothemund

Nature 525, 401-405 (2016)

Optimized assembly and covalent coupling of single-molecule DNA origami nanoarrays

Ashwin studies how to improve the electrostatic self-assembly of DNA origami onto lithographically patterned silica/silicon surfaces. In addition to the electrostatic bonds, we demonstrate covalent bonds, that do not require high concentration magnesium.

A. Gopinath, P.W.K. Rothemund

ACS Nano 8 (12), 12030-12040 (2014)

Self-assembly of two-dimensional DNA origami lattices using cation-controlled surface diffusion

DNA origami are assembled in two-dimensional lattices depending on the concentration of divalent and monovalent cations.

S. Woo, P.W.K. Rothemund

Nature Communications 5, 4889 (2014)

A single-stranded architecture for cotranscriptional folding of RNA nanostructures

Together with Ebbe Andersen’s lab the origami technique gets ported to the world of RNA, that can be folded during transcription and so genetically encoded.

C. Geary, P.W.K. Rothemund, E.S. Andersen

Science 345, 6198 (2014)

Perspective Self-assembled RNA nanostructures by N.B. Leontis and E. Westhof.

Programmable molecular recognition based on the geometry of DNA nanostructures

We show that we can create geometric arrangements of DNA nanostructures not by using the well-known Waston-Crick complementarity, but by exploiting blunt-end stacking interactions. The DNA origami are designed to have orthogonal binding rules and can assemble in desired larger shapes.

S. Woo, P.W.K. Rothemund

Nature Chemistry 3, 620-627 (2011)

Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templates

DNA origami can be used as a scaffold to assemble carbon nanotubes to create field-effect transistors.

H.T. Maune, S. Han, R.D. Barish, M. Bockrath, W.A. Goddard III, P.W.K. Rothemund, E. Winfree

Nature Nanotechnology 5, 61-66 (2010)

Folding DNA to create nanoscale shapes and patterns

Paul develops the new technique of DNA origami. DNA strands can assemble to form arbitrary nanometric shapes. Learn more here.

P.W.K. Rothemund

Nature 440, 297-302 (2006)

News and Views, The manifold faces of DNA by L.M. Smith.

 

Selected List

Ray optics for gliders
T.D. Ross, D. Osmanović, J.F. Brady, P.W.K. Rothemund
ACS Nano XX, XXX (2022)

Absolute and arbitrary orientation of single molecule shapes
A. Gopinath, C. Thachuk, A. Mitskovets, H.A. Atwater, D. Kirkpatrick, P.W.K. Rothemund
Science 371, 6531 (2021)

Engineering and mapping nanocavity emission via precision placement of DNA origami
A. Gopinath, E. Miyazono, A. Faraon, P.W.K. Rothemund
Nature 525, 401-405 (2016)

Optimized assembly and covalent coupling of single-molecule DNA origami nanoarrays
A. Gopinath, P.W.K. Rothemund
ACS Nano 8 (12), 12030-12040 (2014)

Self-assembly of two-dimensional DNA origami lattices using cation-controlled surface diffusion
S. Woo, P.W.K. Rothemund
Nature Communications 5, 4889 (2014)

A single-stranded architecture for cotranscriptional folding of RNA nanostructures
C. Geary, P.W.K. Rothemund, E.S. Andersen
Science 345, 6198 (2014)

Programmable molecular recognition based on the geometry of DNA nanostructures
S. Woo, P.W.K. Rothemund
Nature Chemistry 3, 620-627 (2011)

Self-assembly of carbon nanotubes into two-dimensional geometries using DNA origami templates
H.T. Maune, S. Han, R.D. Barish, M. Bockrath, W.A. Goddard III, P.W.K. Rothemund, E. Winfree
Nature Nanotechnology 5, 61-66 (2010)

Folding DNA to create nanoscale shapes and patterns
P.W.K. Rothemund
Nature 440, 297-302 (2006)